Endocrine Abstracts

Introduction: Adrenal haemorrhage is rare. There is a broad spectrum of clinical presentation and aetiology of the condition making it challenging to diagnose. Endocrine dysfunction frequently complicates cases of adrenal haemorrhage. Failure to recognise the condition or its complications can lead to devastating consequences for the patient.Methods: All patients referred to our centre with adrenal haemorrhage between 2004 and 2014 were included in this ...

Avascular necrosis is a rare presenting feature of endogenous hypercortisolism. The literature suggests that, if left untreated, complete collapse of the femoral head may ensue, necessitating hip replacement in up to 70% of patients. The majority of described patients with avascular necrosis due to endogenous hypercortisolaemia were treated surgically.Case report: A 36-year-old female, investigated for right leg pain, reported rapid weight gain, easy bru...

A 48-year-old man was referred for investigation of uncontrolled hypertension on four agents (olmesartan, felodipine, hydrochlorothiazide and spironolactone) and a 3 cm right-sided adrenal adenoma (pre-contrast Hounsfield units 25). Endocrine investigation for the hypertension and adrenal mass included: androstenedione 19.9 nmol/l 2.8–10.5) (elevated on two occasions on a Siemens Coat-A-Count assay), DHEA 0.7 μmol/l (2.1–15.2), 1 mg overnight dexamethasone suppr...